Student Projects

Collagen volumetric (bio)printing

We are seeking a highly motivated graduate student with a background in mechanical engineering, chemistry, or biomedical engineering to join our interdisciplinary research team focused on advancing collagen volumetric printing (Master thesis level). Collagen, a major structural protein in the extracellular matrix, is integral to tissue engineering due to its biocompatibility and ability to support cell growth [1]. Traditional 3D bioprinting methods, such as layer-based or extrusion-based printing, are often hindered by long processing times, making them less suitable for cell-laden collagen printing. Volumetric printing, an emerging technology, offers a rapid method for constructing 3D collagen scaffolds [2]. However, this approach faces challenges in achieving high fidelity and resolution at the centimeter scale, primarily due to issues with energy contrast during the printing process, which can lead to overpolymerization and compromise the quality of the constructs [3]. Additionally, the resulting structures often have lower stiffness, risking mechanical integrity during post-processing [4]. This project aims to address these challenges by investigating biocompatible free radical photoinhibitors to enhance energy contrast and improve the fidelity of collagen volumetric printing, alongside strategies to strengthen the mechanical properties of the printed structures. Show detailsaddremove